Project Title:

BIOprinting a Predictable in-vitro Atherosclerosis Disease platform to study the hemodynamics and to develop novel therapeutic
strategies

Acronym:

BioPAD

Partners:

Dr. Franca Scocozza (Dept. of Civil Engineering and Architecture, University of Pavia) [PI], Prof. Michele Conti (Dept. of Civil Engineering and Architecture, University of Pavia) [Project Mentor], Prof. Laura Russo (University of Milano-Bicocca) [Advisor/Collaborator] and Prof. Giovanni Spinella (University of Genova) [Advisor/Collaborator].

UniPV funding:

€ 185.428,00

Funding agency:

Fondazione Cariplo

Duration:

2025-2028 (3 years)

Short description:

BioPAD project aims to biofabricate and validate a 3D in-vitro model of atherosclerotic arteries that closely replicates the native vascular environment. By integrating realistic physiological and pathological features with controlled hemodynamic conditions, the platform will enable the study of endothelial cell inflammation and its relationship with blood flow patterns, providing new insights into the mechanisms driving atherosclerosis.